Innovative Drug Discovery, Focused Drug Development

Astex is a leader in innovative drug discovery and development, committed to the fight against cancer and diseases of the central nervous system. As part of Japan’s leading pharmaceutical company, Otsuka Pharmaceutical Co. Ltd., Astex operates from two sites with drug discovery research headquarters in Cambridge, UK and clinical development headquarters in Pleasanton, California, USA.

  • Rich product portfolio with multiple drugs in clinical development
  • Backed by the resources and commitment of a top 20 pharmaceutical company
  • Productive partnerships and alliances with world-leading academic centres and companies
  • Our developing CNS portfolio will be built around alliances and collaborations with key academic research institutes and leading research charities, and via partnerships with other companies

We are a leader in innovative small-molecule therapeutics with particular expertise in fragment-based drug discovery, the most important advance in discovery chemistry in the last 20 years. Although our discovery platform has been successfully applied to therapeutic targets addressing a variety of disease areas, our primary clinical area of focus is currently cancer.  In addition, we are expanding our capabilities and building expertise in the area of fragment-based drug discovery for diseases of the CNS which we plan to develop through collaboration with our parent company, Otsuka, or with other pharmaceutical company partners.