Discover Astex

Innovative Drug Discovery, Focused Drug Development

Astex is a leader in innovative drug discovery and development, committed to the fight against cancer and diseases of the central nervous system (CNS).

We are a member of one of Japan’s leading pharmaceutical companies, the Otsuka group, and therefore benefit from the resources and commitment of a global pharmaceutical company.

We are pioneers of fragment-based drug discovery (FBDD)

The most important advance in discovery chemistry in the last 20 years. Our FBDD platform, “Pyramid™”, has been successfully applied to therapeutic targets addressing a variety of disease areas. We also have a number of partnered products arising from drug discovery collaborations with major pharmaceutical companies.

Robust proprietary oncology product portfolio
With multiple drugs in mid-late stage clinical development worldwide

Developing a CNS product portfolio
Novel targeted therapeutics for defined neurodegenerative disease populations

Highly collaborative, science-driven culture
Enhanced by an “open innovation” approach with a range of strategic relationships with leading academic research institutes, research charities and via partnerships with other companies

Astex operates from two sites:

  • Drug discovery research headquarters in Cambridge, UK
  • Clinical and product development headquarters in Pleasanton, California, USA