Clinical Pipeline

Below is our pipeline of investigational compounds that are currently in various stages of clinical development.

Phase 1	Phase 2	Phase 3

DNMT inhibitor (Treatment Naïve AML)

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DNMT inhibitor (Relapsed/Refractory AML)

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DNMT inhibitor (Relapsed/Refractory MDS or CMML)

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DNMT inhibitor (Solid Tumors)

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Oral DNMT inhibitor (Hematologic Malignancies)

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Dual IAP Antagonist (Solid Tumors & Lymphomas)

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Extracellular Signal-Related Protein Kinases (ERK 1/2) Inhibitor (Solid Tumors)

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Oral Murine Double Minute 2 (MDM2) antagonist (Solid Tumors)

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