2025 AACR (poster): Orthosteric CDK2 kinase inhibitors have a distinctive profile when compared to genetic perturbation of CDK2 in CCNE1-amplified and non-amplified tumor cell lines

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2025 AACR (poster): Orthosteric CDK2 kinase inhibitors have a distinctive profile when compared to genetic perturbation of CDK2 in CCNE1-amplified and non-amplified tumor cell lines

 

 

2025 AACR (poster): Switching cell fate from senescence to apoptosis by the combination of a p53 corrector with the MDM2 antagonist ASTX295

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2025 AACR (poster): Switching cell fate from senescence to apoptosis by the combination of a p53 corrector with the MDM2 antagonist ASTX295

2024 ALS/MND (poster): Investigating Microglia Mediated Neuroinflammation in Stem Cell Models of C9ORF72 Amyotrophic Lateral Sclerosis

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2024 ALS/MND (poster): Investigating Microglia Mediated Neuroinflammation in Stem Cell Models of C9ORF72 Amyotrophic Lateral Sclerosis

2022 ALS/MND (poster): Investigating the role of neuroinflammation in C9ORF72 ALS using stem cell models

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2022 ALS/MND (poster): Investigating the role of neuroinflammation in C9ORF72 ALS using stem cell models

2024 AD/PD (poster): An assay platform to validate novel direct modulators of β-Glucocerebrosidase

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2024 AD/PD (poster): An assay platform to validate novel direct modulators of β-Glucocerebrosidase

2023 AD/PD (poster): Development of a Cellular Platform to Study Lysosomal Functions in Neurodegeneration

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2023 AD/PD (poster): Development of a Cellular Platform to Study Lysosomal Functions in Neurodegeneration

2024 ENA (poster): Pulsatile Induction of the p53 Pathway by MDM2 Antagonist ASTX295 Shows an Enhanced Therapeutic Index in vivo

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2024 ENA (poster): Pulsatile Induction of the p53 Pathway by MDM2 Antagonist ASTX295 Shows an Enhanced Therapeutic Index in vivo

2024 ENA (poster): A Novel Small-Molecule CBP/p300 HAT Domain Inhibitor Demonstrates Potent In Vivo Activity and a Favourable Safety Profile in Preclinical Species

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2024 ENA (poster): A Novel Small-Molecule CBP/p300 HAT Domain Inhibitor Demonstrates Potent In Vivo Activity and a Favourable Safety Profile in Preclinical Species

2024 ENA (poster): Targeting the Catalytic HAT Domain of CBP/p300 for the Treatment of Hormone-Dependent Breast and Prostate Cancers

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2024 ENA (poster): Targeting the Catalytic HAT Domain of CBP/p300 for the Treatment of Hormone-Dependent Breast and Prostate Cancers

2024 ENA (poster): Identification of Biomarkers Predictive of Response to ASTX295, a Next-Generation MDM2 Antagonist, in Solid Tumors Carrying Wild-type p53

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2024 ENA (poster): Identification of Biomarkers Predictive of Response to ASTX295, a Next-Generation MDM2 Antagonist, in Solid Tumors Carrying Wild-type p53