What’s a good fragment? Fragment-based drug discovery is well-established within many pharmaceutical, biotech, and academic institutions for generating new drugs. In this Essay, the opportunities and challenges for organic chemists to design and synthesize new fragments are described.
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Murray et al.. “Opportunity Knocks: Organic Chemistry for Fragment-Based Drug Discovery (FBDD).” Angewandte Chemie. 3 November 2015. DOI: 10.1002/anie.201506783 .