2025 AACR (poster): Orthosteric CDK2 kinase inhibitors have a distinctive profile when compared to genetic perturbation of CDK2 in CCNE1-amplified and non-amplified tumor cell lines

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2025 AACR (poster): Orthosteric CDK2 kinase inhibitors have a distinctive profile when compared to genetic perturbation of CDK2 in CCNE1-amplified and non-amplified tumor cell lines

 

 

2025 AACR (poster): Switching cell fate from senescence to apoptosis by the combination of a p53 corrector with the MDM2 antagonist ASTX295

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2025 AACR (poster): Switching cell fate from senescence to apoptosis by the combination of a p53 corrector with the MDM2 antagonist ASTX295

Zhang et al; “The identification of functional regions of MEK1 using CRISPR tiling screens”; Commun Biol , 2025

Zhang et al; “The identification of functional regions of MEK1 using CRISPR tiling screens”; Commun Biol , 2025

https://pubmed.ncbi.nlm.nih.gov/40274952/

Sharp et al; “Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function”; Nat Commun., 2025

Sharp et al; “Integrating fragment-based screening with targeted protein degradation and genetic rescue to explore eIF4E function”; Nat Commun., 2025

https://doi.org/10.1038/s41467-024-54356-1

Holvey et al; “Fragment-to-Lead Medicinal Chemistry Publications in 2023”; J. Med. Chem., 2025

Holvey et al; “Fragment-to-Lead Medicinal Chemistry Publications in 2023”; J. Med. Chem., 2025

https://doi.org/10.1021/acs.jmedchem.4c02593

2024 ALS/MND (poster): Investigating Microglia Mediated Neuroinflammation in Stem Cell Models of C9ORF72 Amyotrophic Lateral Sclerosis

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2024 ALS/MND (poster): Investigating Microglia Mediated Neuroinflammation in Stem Cell Models of C9ORF72 Amyotrophic Lateral Sclerosis

2022 ALS/MND (poster): Investigating the role of neuroinflammation in C9ORF72 ALS using stem cell models

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2022 ALS/MND (poster): Investigating the role of neuroinflammation in C9ORF72 ALS using stem cell models

2024 AD/PD (poster): An assay platform to validate novel direct modulators of β-Glucocerebrosidase

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2024 AD/PD (poster): An assay platform to validate novel direct modulators of β-Glucocerebrosidase

2023 AD/PD (poster): Development of a Cellular Platform to Study Lysosomal Functions in Neurodegeneration

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2023 AD/PD (poster): Development of a Cellular Platform to Study Lysosomal Functions in Neurodegeneration