2024 ENA (poster): Targeting the Catalytic HAT Domain of CBP/p300 for the Treatment of Hormone-Dependent Breast and Prostate Cancers

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2024 ENA (poster): Targeting the Catalytic HAT Domain of CBP/p300 for the Treatment of Hormone-Dependent Breast and Prostate Cancers

2024 ENA (poster): Identification of Biomarkers Predictive of Response to ASTX295, a Next-Generation MDM2 Antagonist, in Solid Tumors Carrying Wild-type p53

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2024 ENA (poster): Identification of Biomarkers Predictive of Response to ASTX295, a Next-Generation MDM2 Antagonist, in Solid Tumors Carrying Wild-type p53

Ramos et al; “Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery” Cell Reports, 2024

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Ramos et al; “Proteome-wide CETSA reveals diverse apoptosis-inducing mechanisms converging on an initial apoptosis effector stage at the nuclear periphery” Cell Reports, 2024

https://doi.org/10.1016/j.celrep.2024.114784

2024 ESMO (poster): Activity of ERK1/2 Inhibitor ASTX029 in Patients with Gynecological Malignancies Harboring Genomic Alterations in the MAPK Pathway

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2024 ESMO (poster): Activity of ERK1/2 Inhibitor ASTX029 in Patients with Gynecological Malignancies Harboring Genomic Alterations in the MAPK Pathway

Palmer et al; “Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase” J Med Chem, 2024

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Palmer et al; “Fragment-Based Discovery of a Series of Allosteric-Binding Site Modulators of β-Glucocerebrosidase” J Med Chem, 2024

https://doi.org/10.1021/acs.jmedchem.4c00702

Gustavvson et al; “The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1” Science Advances, 2024

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Gustavvson et al; “The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1” Science Advances, 2024

https://www.science.org/doi/10.1126/sciadv.adk1296?

Ma et al; “Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor” J. Med. Chem. 2024

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Ma et al; “Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor” J. Med. Chem. 2024

https://doi.org/10.1021/acs.jmedchem.4c00572

Mukherjee, et al; “Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design”; Structure. 2024

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Mukherjee, et al; “Protein engineering enables a soakable crystal form of human CDK7 primed for high-throughput crystallography and structure-based drug design”; Structure. 2024

https://doi.org/10.1016/j.str.2024.05.011

2023 ASH (poster): Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma

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2023 ASH (poster): Epigenetic priming by hypomethylation enhances the immunogenic potential of tolinapant in T-cell lymphoma

 

Sanchez-Garcia et al; “CESPED: A benchmark for supervised particle pose estimation in cryo-EM” Physical Review Research. 2024

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Sanchez-Garcia et al; “CESPED: A benchmark for supervised particle pose estimation in cryo-EM” Physical Review Research. 2024

https://doi.org/10.1103/PhysRevResearch.6.023245